6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

• CAS Number: 205171-04-6
• UNSPSC Description: 6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine dibenzoate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/6-chloro-9-2-3-5-tri-o-benzoyl-2-c-methyl-beta-d-ribofuranosyl-9h-purine.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@]1(OC(C2=CC=CC=C2)=O)[C@H](OC(C3=CC=CC=C3)=O)[C@@H](COC(C4=CC=CC=C4)=O)O[C@H]1N5C=NC6=C5N=CN=C6Cl
• Molecular Weight: 613.02
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported