LM22A-4

• UNSPSC Description:

  LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research.

• Target Antigen:

  Trk Receptor

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/LM22A-4.html

• Purity:

  98.53

• Solubility:

  DMSO : ≥ 29 mg/mL|H2O : ≥ 50 mg/mL

• Smiles:

  O=C(C1=CC(C(NCCO)=O)=CC(C(NCCO)=O)=C1)NCCO

• Molecular Weight:

  339.34

• References & Citations:

  [1]Yu G, et al. Protective effects of LM22A-4 on injured spinal cord nerves. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6526-32. eCollection 2015.|[2]Kajiya M, et al. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr;19(2):245-52

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  37988-18-4