Products for Research Use Only
RegisterLogin

NH2-PEG2-C2-Boc

CAT: 0804-HY-42149-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-42149-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2].
CAS Number
756525-95-8
UNSPSC
12352203
Hazard Statement
H302
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-peg2-c2-boc.html
Purity
99.62
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NCCOCCOCCC(OC(C)(C)C)=O
Molecular Formula
C11H23NO4
Molecular Weight
233.30
Precautions
H302
References & Citations
[1]Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 24;62 (2) :941-964.|[2]Joshua D. Thomas, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Non-cleavable Linker; PEG Linkers

Related Products

CatalogName
HY-W008474-01Boc-NH-PEG2-C2-NH2
HY-135804-01NH2-PEG3-C2-Boc
HY-W017970-01Boc-C2-NH2
HY-W336455-01Cbz-PEG2-C2-NH2
HY-129703Thalidomide-PEG2-C2-NH2
HY-W096132-01Dimethylamino-PEG2-C2-NH2
HY-130712NH2-C2-amido-C2-Boc
HY-42427-01NH2-PEG2-CH2-Boc
HY-140425Boc-Aminooxy-PEG1-C2-NH2
HY-42776-01NH2-PEG3-C2-NH-Boc

Alternative Products

CatalogName
T16311-01NH2-PEG2-C2-Boc
T16659-01Boc-NH-PEG2-C2-NH2
GTR19224850-01Thalidomide-PEG2-C2-NH2
GTR19275574-01Cbz-PEG2-C2-NH2
T40806-01Dimethylamino-PEG2-C2-NH2
T39358NH2-PEG2-CH2-Boc
abx186575-01Boc-NH-PEG2-NH2
MBS3615590-01Mal-PEG2-C2-Boc
OR1031806-01Iodo-PEG2-C2-Boc
GTR19215995-01Acid-PEG2-C2-Boc

Popular Products