Latent TGF beta 1/TGFB1, Mouse (HEK293, His)
CAT:
804-HY-P78360-04
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Latent TGF beta 1/TGFB1, Mouse (HEK293, His)
- UNSPSC Description: Transforming growth factor beta-1 proprotein is the precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains. TGF beta 1/TGFB1 Protein, Mouse (HEK293, His) is a recombinant protein (L30-S390) produced by HEK293 cells with His tag[1][2].
- Type: Recombinant Proteins
- Assay Protocol: https://www.medchemexpress.com/cytokines/tgf-beta-1-tgfb1-protein-mouse-hek293-his.html
- Purity: 97.00
- Smiles: LSTCKTIDME LVKRKRIEAI RGQILSKLRL ASPPSQGEVP PGPLPEAVLA LYNSTRDRVA GESADPEPEP EADYYAKEVT RVLMVDRNNA IYEKTKDISH SIYMFFNTSD IREAVPEPPL LSRAELRLQR LKSSVEQHVE LYQKYSNNSW RYLGNRLLTP TDTPEWLSFD VTGVVRQWLN QGDGIQGFRF SAHCSCDSKD NKLHVEINGI SPKRRGDLGT IHDMNRPFLL LMATPLERAQ HLHSSRHRRA LDTNYCFSST EKNCCVRQLY IDFRKDLGWK WIHEPKGYHA NFCLGPCPYI WSLDTQYSKV LALYNQHNPG ASASPCCVPQ ALEPLPIVYY VGRKPKVEQL SNMIVRSCKC S
- Molecular Weight: Approximately 11 & 40 & 51 kDa due to the glycosylation
- References & Citations: [1]K. Miyazono, et al. A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1. The EMBO Journal (1991)10:1091-1101.|[2]M Selvakumaran, et al. The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells. Mol Cell Biol. 1994 Apr;14(4):2352-60.|[3]Chambaz E.M., et al. Transforming Growth Factor-βs: A Multifunctional Cytokine Family. Implication in the Regulation of Adrenocortical Cell Endocrine Functions. 1991. |[4]Dulce Maroni, et al. TGFB1 disrupts the angiogenic potential of microvascular endothelial cells of the corpus luteum. Cell Sci. 2011 Jul 15;124(Pt 14):2501-10.|[5]Justin Rustenhoven, et al. TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function. Justin Rustenhoven. 2016 Feb 11;13:37.|[6]Kai Zhang, et al. Essential role of microglial transforming growth factor-β1 in antidepressant actions of (R)-ketamine and the novel antidepressant TGF-β1. Transl Psychiatry. 2020 Jan 27;10(1):32.
- Shipping Conditions: Blue Ice
- Storage Conditions: Stored at -20°C for 2 years