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AHR-13268D

CAT: 0804-HY-123432Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123432Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AHR-13268D is an oral active antiallergic and antihistaminic agent, with bioavailable approximately 88%. AHR-13268D is a potent inhibitor of histamine release from rat peritoneal mast cells, with the IC50 of 0.51 nM[1].
CAS Number
130838-11-8
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ahr-13268d.html
Smiles
O=C(C1=CC=C(C=C1)OCCCN2CCC(CC2)C(C3=CC=C(C=C3)F)(O)C4=CC=C(C=C4)F)O[Na]
Molecular Formula
C28H28F2NNaO4
Molecular Weight
503.51
References & Citations
[1]J C Nolan, et al. The in vivo and in vitro activity of AHR-13268D, a new antiallergic/antihistaminic agent. Agents Actions. 1990 Nov;31 (3-4) :210-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported