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SB251023

CAT: 0804-HY-119497Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119497Size:1 Each
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Description
SB251023 is a β3-adrenergic receptor agonist with pEC50 values of 7.14 and 6.91 for the β3a- and β3b-adrenergic receptors, respectively. SB251023 is capable of modulating cyclic AMP levels and extracellular acidification rate (EAR) in cells. It has potential application value in the study of cardiovascular diseases and metabolic-related disorders[1].
CAS Number
208842-53-9
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sb251023.html
Smiles
O=P(COC1=CC=C(C=C1)CC2(CCCC2)NC[C@@H](COC3=CC=C(C=C3)O)O)(O)C4=CC=CC=C4
Molecular Formula
C28H34NO6P
Molecular Weight
511.55
References & Citations
[1]Hutchinson D S, et al. Mouse β3a‐and β3b‐adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways[J]. British journal of pharmacology, 2002, 135 (8) : 1903-1914.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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