Iprobenfos

• Description:

  Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H411

• Target:

  Cholinesterase (ChE) ; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/iprobenfos.html

• Purity:

  99.87

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=P(OC(C)C)(SCC1=CC=CC=C1)OC(C)C

• Molecular Formula:

  C13H21O3PS

• Molecular Weight:

  288.34

• Precautions:

  H302, H411

• References & Citations:

  [1]Jee-Hyun Jung, et al. Characterization of Cholinesterases in Marbled Sole, Limanda Yokohamae, and Their Inhibition in Vitro by the Fungicide Iprobenfos. Mar Environ Res. 2007 Jun;63 (5) :471-8.|[2]Zuo-Qian Wang, et al. A Putative Zn 2 Cys 6 Transcription Factor Is Associated With Isoprothiolane Resistance in Magnaporthe oryzae. Front Microbiol. 2018 Oct 31;9:2608.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  26087-47-8