Human VEGFR2

Human VEGFR2 _x000D_ Catalog number: B2013637_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 µg_x000D_ Molecular Weight or Concentration: 116 g/mol_x000D_ Supplied as: Lyophilized_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20¬∞C_x000D_ Keywords: Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Sun J, Huang W, Yang SF, Zhang XP, Yu Q, Zhang ZQ, Yao J, Li KR, Jiang Q, Cao C. G√鬱i1 and G√鬱i3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis Theranostics. 2018 Sep 9;8(17):4695-4709._x000D_ 2: Zhou HJ, Xu Z, Wang Z, Zhang H, Zhuang ZW, Simons M, Min W. SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis Nat Commun. 2018 Aug 17;9(1):3303._x000D_ 3: Liu K, Ren T, Huang Y, Sun K, Bao X, Wang S, Zheng B, Guo W. Apatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma Cell Death Dis. 2017 Aug 24;8(8):e3015._x000D_ 4: Zhong M, Li N, Qiu X, Ye Y, Chen H, Hua J, Yin P, Zhuang G. TIPE regulates VEGFR2 expression and promotes angiogenesis in colorectal cancer Int J Biol Sci. 2020 Jan 1;16(2):272-283._x000D_ 5: Chen L, Xie X, Wang T, Xu L, Zhai Z, Wu H, Deng L, Lu Q, Chen Z, Yang X, Lu H, Chen YG, Luo S. ARL13B promotes angiogenesis and glioma growth by activating VEGFA-VEGFR2 signaling Neuro Oncol. 2023 May 4;25(5):871-885._x000D_ 6: Shah AA, Kamal MA, Akhtar S. Tumor Angiogenesis and VEGFR-2: Mechanism, Pathways and Current Biological Therapeutic Interventions Curr Drug Metab. 2021;22(1):50-59._x000D_ 7: Xuan ZX, Li LN, Zhang Q, Xu CW, Yang DX, Yuan Y, An YH, Wang SS, Li XW, Yuan SJ. Fully human VEGFR2 monoclonal antibody BC001 attenuates tumor angiogenesis and inhibits tumor growth Int J Oncol. 2014 Dec;45(6):2411-20._x000D_ 8: Englisch A, Altvater B, Kailayangiri S, Hartmann W, Rossig C. VEGFR2 as a target for CAR T cell therapy of Ewing sarcoma Pediatr Blood Cancer. 2020 Oct;67(10):e28313._x000D_ 9: Bosma EK, Darwesh S, Zheng JY, van Noorden CJF, Schlingemann RO, Klaassen I. Quantitative Assessment of the Apical and Basolateral Membrane Expression of VEGFR2 and NRP2 in VEGF-A-stimulated Cultured Human Umbilical Vein Endothelial Cells J Histochem Cytochem. 2022 Aug;70(8):557-569._x000D_ 10: Liu F, Wu W, Wu K, Chen Y, Wu H, Wang H, Zhang W. MiR-203 Participates in Human Placental Angiogenesis by Inhibiting VEGFA and VEGFR2 Expression Reprod Sci. 2018 Mar;25(3):358-365. _x000D_ _x000D_ Products Related to Human VEGFR2 can be found at Proteins

Catalog Number: B2013637 (10 µg)

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