Anisatin

CAT: 0804-HY-N9506-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N9506-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM[1].
CAS Number
[5230-87-5]
UNSPSC
12352005
Hazard Statement
H300+H330
Target
GABA Receptor
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anisatin.html
Purity
99.0
Smiles
O[C@]12[C@]3([C@@H](C[C@H]2O)C)C[C@@H](OC([C@@H]3O)=O)[C@](O)([C@]14C(OC4)=O)C
Molecular Formula
C15H20O8
Molecular Weight
328.31
Precautions
P260-P264-P270-P271-P284-P304+P340-P330-P403+P233-P405-P501
References & Citations
[1]Ikeda T, et al. Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons. Br J Pharmacol. 1999;127 (7) :1567-1576.|[2]Bao X, et al. Bioavailability and Pharmacokinetics of Anisatin in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry. Biomed Res Int. 2020;2020:8835447. Published 2020 Dec 23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W015342-01Methyl anisate
HY-W097777-01Anisoin
HY-N2269-01P-Hydroxyphenethyl anisate
HY-W015342R-01Methyl anisate (Standard)

Alternative Products

CatalogName
MBS5802095Anisatin

Popular Products