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VMIP-II (1-21)

CAT: 0804-HY-P4109Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P4109Size:1 Each
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Description
VMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM) [1].
CAS Number
265650-93-9
Product Name Alternative
NT21MP; V1 peptide
UNSPSC
12352209
Target
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vmip-ii-1-21.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CS)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@H](CO)NC([C@H](C)NC(CNC([C@@H](N)CC(C)C)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O
Molecular Formula
C108H169N33O27S2
Molecular Weight
2425.84
References & Citations
[1]Zhou N, ey al. A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II. Biochemistry. 2000 Apr 4;39 (13) :3782-7.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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