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Caraphenol A

CAT: 0804-HY-N3540-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3540-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells[1]. Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC50s of 5.9 μM and 12.1 μM, respectively[2].
CAS Number
354553-35-8
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/caraphenol-a.html
Purity
99.71
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[H][C@]12[C@@H](OC3=C1C([C@@]4([C@H](OC5=C4C(C6=C(OC7=C6C2=CC(O)=C7)C8=CC=C(O)C=C8)=CC(O)=C5)C9=CC=C(O)C=C9)[H])=CC(O)=C3)C%10=CC=C(O)C=C%10
Molecular Formula
C42H28O9
Molecular Weight
676.67
References & Citations
[1]Ozog S, et al. Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. Blood. 2019 Oct 17;134 (16) :1298-1311.|[2]Niu W, et al. Discovery of selective cystathionine β-synthase inhibitors by high-throughput screening with a fluorescent thiol probe. Medchemcomm. 2016 Nov 15;8 (1) :198-201.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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