Products for Research Use Only
RegisterLogin

Captopril (Standard)

CAT: 0804-HY-B0368R-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0368R-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Captopril (Standard) is the analytical standard of Captopril. This product is intended for research and analytical applications. Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM[1][2][3].
CAS Number
62571-86-2
Product Name Alternative
SQ 14225 (Standard)
UNSPSC
12352005
Hazard Statement
H317, H361
Target
Angiotensin-converting Enzyme (ACE) ; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/captopril-standard.html
Purity
99.75
Smiles
O=C(O)[C@H]1N(C([C@H](C)CS)=O)CCC1
Molecular Formula
C9H15NO3S
Molecular Weight
217.29
Precautions
H317, H361
References & Citations
[1]Tzakos, A.G., et al., The molecular basis for the selection of captopril cis and trans conformations by angiotensin I converting enzyme. Bioorg Med Chem Lett, 2006. 16 (19) : p. 5084-7.|[2]Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41 (3) : p. 207-24.|[3]Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64 (11) :2263-2268.|[4]Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.|[5]Li N, et al. Simplified captopril analogues as NDM-1 inhibitors. Bioorg Med Chem Lett. 2014;24 (1) :386-389.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-123068RCaptopril disulfide (Standard)
HY-W015332RCaptopril EP Impurity D (Standard)
HY-137769RCaptopril EP Impurity C (Standard)
HY-137768RCaptopril EP Impurity B (Standard)
HY-137772RCaptopril EP Impurity E (Standard)
HY-B0368-01Captopril
HY-B0368SCaptopril-d3
HY-B0368ACaptopril (hydrochloride)
HY-CE01272Captopril-CoA
HY-123068-01Captopril disulfide

Alternative Products

CatalogName
FC19675-01Captopril

Popular Products