ARP

• Description :

  ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 104 nucleotides) [1].

• CAS Number :

  [139585-03-8]

• Product Name Alternative :

  Aldehyde reactive probe

• UNSPSC :

  12352200

• Target :

  Fluorescent Dye

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/arp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NOCC(NNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O

• Molecular Formula :

  C12H21N5O4S

• Molecular Weight :

  331.39

• References & Citations :

  [1]Kubo K, et al., A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion. Biochemistry. 1992 Apr 14;31 (14) :3703-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported