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Megestrol-d5

CAT: 0804-HY-B1834S1-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1834S1-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Megestrol-d5 is the deuterium labeled Megestrol. Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis[1][2].
UNSPSC
12352211
Target
Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C(C([2H])([2H])[2H])=O)(O)CC[C@@]1([H])[C@]3([H])C=C(C)C4=CC(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC2)=O
Molecular Formula
C22H25D5O3
Molecular Weight
347.50
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Garcia JM, et al. Off-Label Megestrol in Patients with Anorexia-Cachexia Syndrome Associated with Malignancy and Its Treatments. Am J Med. 2018 Jun;131 (6) :623-629.e1.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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