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Laromustine

CAT: 0804-HY-10537-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10537-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Laromustine (VNP40101M) is a compound with antitumor activity. The mechanism of action of Laromustine mainly involves DNA alkylation and DNA repair inhibition. Laromustine can be used for bone marrow transplantation in patients with acute myeloid leukemia and cancer[1].
CAS Number
173424-77-6
Product Name Alternative
VNP40101M
UNSPSC
12352211
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/laromustine.html
Smiles
O=C(N(S(=O)(C)=O)N(S(=O)(C)=O)CCCl)NC
Molecular Formula
C6H14ClN3O5S2
Molecular Weight
307.78
References & Citations
[1]Nassar A E F, et al. An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes[J]. Drug metabolism and disposition, 2009, 37 (9) : 1922-1930.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
BUP03412-01Laromustine

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