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Broflanilide

CAT: 0804-HY-108689-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108689-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM[1].
CAS Number
1207727-04-5
UNSPSC
12352005
Hazard Statement
H301, H312, H330, H410
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Broflanilide.html
Purity
98.95
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
FC(F)(F)C(F)(C1=CC(C(F)(F)F)=C(NC(C2=C(C(N(C)C(C3=CC=CC=C3)=O)=CC=C2)F)=O)C(Br)=C1)C(F)(F)F
Molecular Formula
C25H14BrF11N2O2
Molecular Weight
663.28
Precautions
H301, H312, H330, H410
References & Citations
[1]Nakao T, et al. Broflanilide: A meta-diamide insecticide with a novel mode of action. Bioorg Med Chem. 2016 Feb 1;24 (3) :372-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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