Products for Research Use Only
RegisterLogin

Bopindolol

CAT: 0804-HY-B1562-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1562-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Bopindolol ((±) -Bopindolol) is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol is a proagent of Pindolol. Bopindolol can be used for essential and renovascular hypertension research.
CAS Number
62658-63-3
Product Name Alternative
(±) -Bopindolol
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Renin
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bopindolol.html
Solubility
10 mM in DMSO
Smiles
CC(N1)=CC2=C1C=CC=C2OCC(OC(C3=CC=CC=C3)=O)CNC(C)(C)C
Molecular Formula
C23H28N2O3
Molecular Weight
380.48
References & Citations
[1]Harron DW, et al. Bopindolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1991 Jan;41 (1) :130-49. |[2]H Tanaka, et al. Hypotensive effect of bopindolol in pithed rats. Gen Pharmacol. 1993 Mar;24 (2) :373-5.|[3]Y Hosohata, et al. Bopindolol is a slowly dissociating beta 1-adrenoceptor antagonist when compared to other beta-blockers. Biol Pharm Bull. 1995 Aug;18 (8) :1066-71.|[4]Nagatomo T, et al. Bopindolol: pharmacological basis and clinical implications. Cardiovasc Drug Rev. 2001 Spring;19 (1) :9-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

Alternative Products

CatalogName
FB37307-01Bopindolol
T35871-01Bopindolol (malonate)
MBS387797-01Bopindolol malonate
sc-503926Rac Bopindolol
T63356-01Bopindolol fumarate
TRC-B675402-10MGrac Bopindolol-d9
A13398-1000Bopindolol malonate 1000mg
A13398-500Bopindolol malonate 500mg
A13398-250Bopindolol malonate 250mg
A13398-100Bopindolol malonate 100mg

Popular Products