Raloxifene

• UNSPSC Description:

  Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/raloxifene.html

• Smiles:

  O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4

• Molecular Weight:

  473.58

• References & Citations:

  [1]Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439.|[2]Xu H, et al. Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomed Pharmacother. 2019;112:108650.ACS Omega. 2023 Jun 14.|J Pharmaceut Biomed. 2020, 113870.|Mol Neurobiol. 2024 Oct 2.|Cell Rep Methods. 2023 Oct 23;3(10):100599.|Eberhard Karls Universität Tübingen. 2021 Aug.|Free Radic Biol Med. 2017 Apr 10;108:404-417.|Med Sci Monit. 2019 Apr 29;25:3146-3153.|Oxid Med Cell Longev. 2021 Mar 20;2021:6699054.|PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. |Research Square Preprint. 2020 Nov 4;rs.3.rs-100914.|Viruses. 2021 Jun 28;13(7):1255.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  84449-90-1