Beaucage reagent

• UNSPSC Description:

  Beaucage reagent is found to be potent in causing DNA cleavage[1][2][3].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Beaucage-reagent.html

• Purity:

  98.0

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : 0.14 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC=CC=C12)SS2(=O)=O

• Molecular Weight:

  200.24

• References & Citations:

  [1]Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent. Org Biomol Chem. 2010 Mar 21;8(6):1293-5.|[2]C. F. H. Allen, et al. Working with Hazardous Chemicals. Organic Syntheses, Coll. Vol. 2, 1943, 580.|[3] Stec W J, et al. Bis (O, O-diisopropoxy phosphinothioyl) disulfide-a highly efficient sulfurizing reagent for cost-effective synthesis of oligo (nucleoside phosphorothioate) s[J]. Tetrahedron letters, 1993, 34(33): 5317-5320.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  66304-01-6