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Uvagrandol

CAT: 0804-HY-N10606Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10606Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Uvagrandol potently inhibits α-glucosidase and porcine lipase (IC50: 15.2 μM, 11.2 μM respectively) . Uvagrandol can be used in the research of Type 2 diabetes and obesity[1].
UNSPSC
12352005
Target
Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/uvagrandol.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@@H]1CC[C@H]([C@@H]([C@]1(CO)O)O)OC(C2=CC=CC=C2)=O)C3=CC=CC=C3
Molecular Formula
C21H22O7
Molecular Weight
386.40
References & Citations
[1]Galal KA, et al. Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro. J Med Chem. 2022 Oct 13;65 (19) :13172-13197.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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