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16a-Hydroxydehydroisoandrosterone

CAT: 0804-HY-113031-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113031-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
16a-Hydroxydehydroisoandrosterone (16α-Hydroxy-DHEA) is a metabolite of the endogenous steroid hormone dehydroepiandrosterone. 16α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosterone via 16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol.
CAS Number
1232-73-1
Product Name Alternative
16α-Hydroxy-DHEA; 16α-OH-DHEA; 16α-hydroxy DHEA
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/16a-hydroxydehydroisoandrosterone.html
Purity
98.40
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@@H](O)CC2)([H])[C@@]4([H])[C@@](C)(C([C@H](O)C4)=O)CC3
Molecular Formula
C19H28O3
Molecular Weight
304.42
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Miller, et al. Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450. Drug. Metab. Dispos. 32 (3), 305-313 (2004) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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