2-Methylthio isopentenyladenosine

2-Methylthio isopentenyladenosine

• CAS Number: 20859-00-1
• UNSPSC Description: 2-Methylthio isopentenyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-methylthio-isopentenyladenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NC/C=C(C)/C)=NC(SC)=N3
• Molecular Weight: 381.45
• References & Citations: [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.|[2]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported