Penconazole

• Description:

  Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H361, H400, H410

• Target:

  Cholinesterase (ChE) ; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/penconazole.html

• Concentration:

  10mM

• Purity:

  98.91

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CCCC (C1=CC=C (Cl) C=C1Cl) CN2N=CN=C2

• Molecular Formula:

  C13H15Cl2N3

• Molecular Weight:

  284.18

• Precautions:

  H302, H361, H400, H410

• References & Citations:

  [1]Husak VV, et al. Acute exposure to the penconazole-containing fungicide Topas partially augments antioxidant potential in goldfish tissues. Comp Biochem Physiol C Toxicol Pharmacol. 2017;193:1-8.|[2]Chaâbane M, et al. Penconazole alters redox status, cholinergic function, and membrane-bound ATPases in the cerebrum and cerebellum of adult rats. Hum Exp Toxicol. 2017;36 (8) :854-866.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE

• CAS Number:

  66246-88-6