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Cinoxacin

CAT: 0804-HY-B1085-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-B1085-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis[1][2].
CAS Number
28657-80-9
Product Name Alternative
Compound 64716
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Cinoxacin.html
Purity
99.99
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
O=C(C1=NN(CC)C2=C(C=C3C(OCO3)=C2)C1=O)O
Molecular Formula
C12H10N2O5
Molecular Weight
262.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Scavone JM, et al. Cinoxacin: mechanism of action, spectrum of activity, pharmacokinetics, adverse reactions, and therapeutic indications. Pharmacotherapy. 1982 Sep-Oct;2 (5) :266-72. |[2]W E Wick, et al. Compound 64716, a new synthetic antibacterial agent. Antimicrob Agents Chemother. 1973 Oct;4 (4) :415-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone

Chemical Information

Cinoxacin

Cinoxacin is a member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections. It has a role as an antiinfective agent and an antibacterial drug. It is an oxo carboxylic acid, an oxacycle and a member of cinnolines.

CAS Number28657-80-9
PubChem CID2762
IUPAC Name1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
Molecular FormulaC12H10N2O5
Molecular Weight262.22
XLogP2.1
Topological Polar Surface Area88.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Heavy Atom Count19
Formal Charge0
Complexity449
SMILES
CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3
InChI
InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)
InChIKey
VDUWPHTZYNWKRN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cinoxacin
CAS: 28657-80-9
CID: 2762
Formula: C12H10N2O5
MW: 262.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight262.22
XLogP32.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass262.05897142
Monoisotopic Mass262.05897142
Topological Polar Surface Area88.4 Ų
Heavy Atom Count19
Formal Charge0
Complexity449
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
RM-C323000-01Cinoxacin
A17377-50Cinoxacin 50mg
TRC-C475702-100MGCinoxacin-d5
A17377-100Cinoxacin 100mg
A17377-25Cinoxacin 25mg
50023-AATCinoxacin-BSA Conjugate
50022-AATCinoxacin-HRP Conjugate

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