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Atoxifent

CAT: 0804-HY-163667Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163667Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atoxifent is a potent μ-opioid receptor agonist (EC50=0.39 nM) . These receptors are found in brain regions that control pain, emotions, habitual learning, and cognition. Atoxifent exhibits strong analgesic effects and a lower risk of respiratory depression. Atoxifent can be used for research in opioid pharmacology and signal transduction[1].
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atoxifent.html
Smiles
OC1=CC(N2[C@H]3CC[C@@H]2CN(CCCC4=CC=CC=C4)C3)=CC=C1
Molecular Formula
C21H26N2O
Molecular Weight
322.44
References & Citations
[1]Vu L Y, et al. Searching for Synthetic Opioid Rescue Agents: Identification of a Potent Opioid Agonist with Reduced Respiratory Depression[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19262756-01Atoxifent

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