Bromperidol

• Description:

  Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin[1][2].

• Product Name Alternative:

  R-11333

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial; Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Bromperidol.html

• Purity:

  99.83

• Solubility:

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C (C1=CC=C (F) C=C1) CCCN2CCC (O) (C3=CC=C (Br) C=C3) CC2

• Molecular Formula:

  C21H23BrFNO2

• Molecular Weight:

  420.32

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35 (6) :670-84.|[2]Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55 (8) :3861-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  D2 Receptor

• CAS Number:

  10457-90-6