Nerol

• UNSPSC Description:

  Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2].

• Target Antigen:

  Apoptosis; Endogenous Metabolite; Fungal; Mitochondrial Metabolism; Reactive Oxygen Species

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nerol.html

• Purity:

  98.97

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  C/C(C)=C/CC/C(C)=C\CO

• Molecular Weight:

  154.25

• References & Citations:

  [1]Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca²⁺ overload in saprotrophic fungus Aspergillus flavus. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672.|[2]Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca²⁺ and ROS in Candida albicans. Int J Biochem Cell Biol. 2017 Apr;85:114-122.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  106-25-2