(R)-Metoprolol-d7

(R)-Metoprolol-d7

• CAS Number: 1292907-84-6
• UNSPSC Description: (R)-Metoprolol-d7 is the deuterium labeled Metoprolol. Metoprolol (Toprol) is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension[1][2].
• Target Antigen: Adrenergic Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
• Field of Research: Cardiovascular Disease; Endocrinology
• Solubility: 10 mM in DMSO
• Smiles: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NC[C@@H](O)COC1=CC=C(C=C1)CCOC
• Molecular Weight: 274.41
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Benfield P, et al. Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. Drugs. 1986 May;31(5):376-429.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported