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Linavonkibart

CAT: 0804-HY-P990069-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P990069-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer[1].
CAS Number
2640981-30-0
Product Name Alternative
SRK-181
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/linavonkibart.html
Purity
95.69
Solubility
10 mM in DMSO
Smiles
[Linavonkibart]
Molecular Weight
(144.7 kDa)
References & Citations
[1]Brian T Welsh, et al. Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors. Int J Toxicol. 2021 May-Jun;40 (3) :226-241.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

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