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Recombinant Human Interleukin-19

CAT: 0355-AP60014Size: InquireDry Ice: NoHazardous: No
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CAT#:0355-AP60014Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human Interleukin-19 (IL-19) is encoded by the IL19 gene, which is located on the chromosome 1. The protein belongs to the IL-10 family that includes IL-10, IL-20, IL-22, IL-24, and IL-26. As a monomer made of seven amphipathic helices, IL-19 has a helical bundle and shares the same cell surface receptor (IL-20R) with IL-20 and IL-24. It may play some important roles in inflammatory responses because it up-regulates IL-6 and TNF-alpha and induces apoptosis.
Product Name Alternative
Melanoma Differentiation-associated Protein-like Protein, NG.1
Gene ID
29949
UniProt
Q9UHD0
Target
LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA
Purification
> 95 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ug of rHuIL-19 as determined by LAL method.
Bioactivity
5
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Host or Source
Escherichia coli

UniProtKB · Q9UHD0

Interleukin-19

IL19_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UHD0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL19
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-19
EC number
—
Processing
Precursor
Secondary accessions
B6VEV9, Q5VUT3, Q96QR4, Q9NUA0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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