α-Pyridone

• Description:

  α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2- (phenylsulfinyl) acetamide to α, β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds[1][2].

• Product Name Alternative:

  2-Pyridone

• UNSPSC:

  12352005

• Hazard Statement:

  H301

• Target:

  Bacterial; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Infection; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/alpha-pyridone.html

• Purity:

  99.88

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1C=CC=CN1

• Molecular Formula:

  C5H5NO

• Molecular Weight:

  95.10

• Precautions:

  H301

• References & Citations:

  [1]Masaya Fujii, et al., 2-Pyridone Synthesis Using 2- (Phenylsulfinyl) acetamide. Org. Lett. 2013, 15, 1, 232–234. |[2]Mostafa M.K. Amer, et al., Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds. Journal of Saudi Chemical Society, 2021.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  142-08-5