Bendazol

CAT: 0804-HY-B2141-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B2141-01Size:500 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Bendazol is an orally effective antihypertensive agent. Bendazol acts directly on vascular smooth muscle to dilate blood vessels and reduce peripheral resistance, thereby improving blood circulation. Bendazol significantly inhibits the development of myopia in rabbit models. Bendazol can regulate kidney function by increasing the activity of NO synthase in the rat model of nephrogenic hypertension. In addition, Bendazol has an effect on sexual behavior and spermatogenesis in male rats[1][2][3].
CAS Number
[621-72-7]
UNSPSC
12352005
Hazard Statement
H302
Target
HIF/HIF Prolyl-Hydroxylase; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/Bendazol.html
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(CC2=CC=CC=C2)=NC3=CC=CC=C3N1
Molecular Formula
C14H12N2
Molecular Weight
208.26
Precautions
H302
References & Citations
[1]Eliseeva EV, et al. Effect of Hypotensive Drugs on Dynamics of Nitroxide-Producing Renal Function in Rats with Nephrogenic Hypertension. Bull Exp Biol Med. 2017 Jan;162 (3) :357-361.|[2]Tong L, et al. Topical bendazol inhibits experimental myopia progression and decreases the ocular accumulation of HIF-1α protein in young rabbits. Ophthalmic Physiol Opt. 2020 Sep;40 (5) :567-576.|[3]Kuzubova EA, et al. [Effect of dibazol (bendazol) on the generative function in rats]. Eksp Klin Farmakol. 2007 Mar-Apr;70 (2) :37-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HIF-1α

Related Products

CatalogName
HY-17480-01Bendazac
HY-17480R-01Bendazac (Standard)
HY-B2165-01Bendazac L-Lysine
HY-132437S-016-Hydroxy Bentazon-d7
HY-B2165R-01Bendazac L-Lysine (Standard)
HY-23184-011-Brom-4,5-dimethyl-2-nitro-benzol

Alternative Products

CatalogName
BUP17648Bendazol
RM-B053000-01Bendazol; Dibazole
413672Bendazol HCl
413671Bendazol (free base)

Popular Products