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Lunsekimig

CAT: 0804-HY-P990748-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P990748-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lunsekimig (SAR443765) is an anti-TSLP/IL13/ALB nonobody composed of 5 sequentially linked variable region heavy chains. Lunsekimig decreases blood eosinophils and lowers plasma levels of IL-5, eotaxin-3, and IgE. Lunsekimig also improves lung function. Lunsekimig can be used for the study and treatment of type 2 inflammatory asthma[1][2].
CAS Number
2770858-49-4
Product Name Alternative
SAR443765
UNSPSC
12352203
Target
Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lunsekimig.html
Purity
98.00
Molecular Weight
(69.702 kDa)
References & Citations
[1]Deiteren A, et al. A first-in-human, single and multiple dose study of lunsekimig, a novel anti-TSLP/anti-IL-13 NANOBODY® compound, in healthy volunteers. Clin Transl Sci. 2024 Jun;17 (6) :e13864. |[2]Kourid MI, et al. Lunsekimig's bispecific targeting of IL-13 and TSLP in asthma: dual targets for synergistic effects? Eur Respir J. 2025 Apr 24;65 (4) :2500153
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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