Martynoside

• Description :

  Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU) -induced cell death and inflammation response by down-regulating the TNF signaling pathway[1].Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer, Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/martynoside.html

• Purity :

  99.41

• Solubility :

  DMSO : 25 mg/mL (ultrasonic)

• Smiles :

  COC(C=C1/C=C/C(O[C@H]([C@H](O[C@H]([C@@H]2O)OCCC3=CC(O)=C(C=C3)OC)CO)[C@@H]2O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)=O)=C(C=C1)O

• Molecular Formula :

  C31H40O15

• Molecular Weight :

  652.64

• References & Citations :

  [1]Hong M, et al. Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity. Biomed Pharmacother. 2021;138:111501.|[2]Papoutsi Z, et al. Acteoside and martynoside exhibit estrogenic/antiestrogenic properties. J Steroid Biochem Mol Biol. 2006;98 (1) :63-71.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [67884-12-2]