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DFAME

CAT: 0804-HY-W073524-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W073524-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DFAME is a red fluorophore (Ex = 508 nm, Em = 641 nm) . DFAME binds to Beetroot and Corn (dimeric fluorescent RNA aptamers) to form Beetroot-DFAME (Kd = 460 nM) and Corn-DFAME (Kd = 3600 nM) . Beetroot-DFAME and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research[1].
CAS Number
1420815-55-9
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dfame.html
Purity
98.58
Solubility
10 mM in DMSO
Smiles
O=C(OC)/C=C\C1=N/C(C(N1C)=O)=C/C2=CC(F)=C(O)C(F)=C2
Molecular Formula
C15H12F2N2O4
Molecular Weight
322.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiahui Wu, et al. Self-Assembly of Intracellular Multivalent RNA Complexes Using Dimeric Corn and Beetroot Aptamers. J Am Chem Soc. 2022 Mar 30;144 (12) :5471-5477.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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