VPM-p15

CAT: 0804-HY-P10365-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P10365-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6) . The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members[1].
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Adhesion G Protein-coupled Receptors (AGPCRs)
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vpm-p15.html
Purity
98.25
Solubility
DMSO : 15 mg/mL (ultrasonic; warming)
Smiles
[H]N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(C=C1)C)C(NCC(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(O)=O)=O)CC(C)C)=O)CO)=O)[C@H](O)C)=O)CCCNC(N)=N)=O)CO)=O)CC(C)C)=O)=O)CC(C)C)=O)CC(C)C)=O)[C@@H](C)CC)=O)=O)=O)CO)=O)C(C)C
Molecular Formula
C75H126N18O22
Molecular Weight
1631.91
Precautions
H302, H315, H319, H335
References & Citations
[1]Sun Y, et al. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology[J]. Journal of Biological Chemistry, 2021, 296.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P3159-01VPM peptide
HY-P3159AVPM peptide (TFA)
HY-P11087P15
HY-P85850P15 INK Antibody (YA5542, Mouse)
HY-13895-01WHI-P154
HY-P81743-01P150 CAF1 Antibody (YA1488, Rabbit)
HY-P84751-01PI 3 Kinase p150 Antibody (YA4448, Mouse)
HY-P83078-01PI 3 Kinase p150 Antibody (YA2823, Rabbit)

Alternative Products

CatalogName
MF-0127181-01VPM-p15
MF-0100252-01VPM-p15 TFA
MBS3847440-01VPM peptide
A22860-1VPM peptide 1mg
A22860-10VPM peptide 10mg
A22860-5VPM peptide 5mg
MF-0126966-01VPM peptide TFA
sc-59205MHC class I (VPM 19)
MF-0127464-01P15
sc-59205 FITCMHC class I (VPM 19) FITC

Popular Products