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Dimercaprol

CAT: 0804-HY-B1285-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1285-01Size:100 mg
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Description
Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning[1].
CAS Number
59-52-9
Product Name Alternative
2,3-Dimercapto-1-propanol; Dithioglycerol
UNSPSC
12352100
Hazard Statement
H301, H315, H319, H335
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dimercaprol.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 16.67 mg/mL (ultrasonic)
Smiles
OCC(S)CS
Molecular Formula
C3H8OS2
Molecular Weight
124.23
Precautions
H301, H315, H319, H335
References & Citations
[1]Kubota S, et al. 2,3 Dimercapto-1-propanol inhibits HIV-1 tat activity, viral production, and infectivity in vitro. AIDS Res Hum Retroviruses. 1990 Jul;6 (7) :919-27.|[2]Ran Tian, et al. Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury. J Neurochem. 2017 Jun;141 (5) :708-720. |[3]Taciane Roza, et al. 2,3-Dimercapto-1-propanol does not alter the porphobilinogen synthase inhibition but decreases the mercury content in liver and kidney of suckling rats exposed to HgCl2. Basic Clin Pharmacol Toxicol. 2005 Apr;96 (4) :302-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

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