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CHAF1B antibody

CAT: 0710-FNab10505Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10505Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Synonyms
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) |Chromatin assembly factor I p60 subunit (CAF-I 60 kDa subunit, CAF-I p60) |M-phase phosphoprotein 7|CHAF1B|CAF1A|CAF1P60|MPHOSPH7|MPP7
UniProt
Q13112
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chromatin assembly factor 1 subunit B
Target
CHAF1B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · Q13112

Chromatin assembly factor 1 subunit B

CAF1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13112
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHAF1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CAF-1 subunit B
EC number
—
Processing
—
Secondary accessions
Q99548
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Biological process

Cell cycleDNA damageDNA repairDNA replication

Molecular function

ChaperoneChromatin regulator

Cellular component

CytoplasmNucleus

Domain

RepeatWD repeat

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