trans-Clopenthixol (dihydrochloride)

trans-Clopenthixol (dihydrochloride)

• CAS Number: 58045-22-0
• UNSPSC Description: trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro[1][2].
• Target Antigen: Antibiotic; Bacterial; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/trans-clopenthixol-dihydrochloride.html
• Purity: 99.98
• Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: OCCN(CC1)CCN1CC/C=C2C3=CC(Cl)=CC=C3SC4=CC=CC=C4/2.[H]Cl.[H]Cl
• Molecular Weight: 473.89
• References & Citations: [1]Kristiansen JE, et al. The susceptibility of Plasmodium falciparum in vitro to chlorpromazine and the stereo-isomeric compounds cis(Z)- and trans(E)-clopenthixol. Acta Pathol Microbiol Immunol Scand B. 1985 Jun;93(3):249-51.|[2]Kristiansen J E, et al. Stereo-isomeric dissociation of the antibacterial and the neuroleptic effect of clopenthixol[J]. Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 1981, 89(6): 437-438.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported