β-Cedrene

• UNSPSC Description:

  β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM[1][2].

• Target Antigen:

  Fungal

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/β-cedrene.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H]1[C@@]23[C@](CC1)([H])C(C)([C@@](C(CC3)=C)([H])C2)C

• Molecular Weight:

  204.35

• References & Citations:

  [1]Ertugrul K, et al. Essential oils from flowers of Centaurea kotschyi var. kotschyi and C. kotschyi var. decumbens from Turkey[J]. Flavour and fragrance journal, 2003, 18(2): 95-97.|[2]Jeong H U, et al. Inhibitory effects of cedrol, β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes[J]. Journal of Toxicology and Environmental Health, Part A, 2014, 77(22-24): 1522-1532.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  546-28-1