β-Cedrene

• Description :

  β-Cedrene ((+) -β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM[1][2].

• CAS Number :

  [546-28-1]

• Product Name Alternative :

  (+) -β-Cedrene

• UNSPSC :

  12352211

• Hazard Statement :

  H410

• Target :

  Fungal

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/β-cedrene.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@H]1[C@@]23[C@](CC1)([H])C(C)([C@@](C(CC3)=C)([H])C2)C

• Molecular Formula :

  C15H24

• Molecular Weight :

  204.35

• Precautions :

  P273-P391-P501

• References & Citations :

  [1]Ertugrul K, et al. Essential oils from flowers of Centaurea kotschyi var. kotschyi and C. kotschyi var. decumbens from Turkey[J]. Flavour and fragrance journal, 2003, 18 (2) : 95-97.|[2]Jeong H U, et al. Inhibitory effects of cedrol, β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes[J]. Journal of Toxicology and Environmental Health, Part A, 2014, 77 (22-24) : 1522-1532.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported