BML-111
CAT:
804-HY-100450-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BML-111
- CAS Number: 78606-80-1
- UNSPSC Description: BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties[1][2].
- Target Antigen: Angiotensin-converting Enzyme (ACE)
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: COVID-19-anti-virus
- Field of Research: Cancer; Inflammation/Immunology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/bml-111.html
- Purity: 98.0
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(OC)CCC[C@H](O)[C@H](O)CO
- Molecular Weight: 192.21
- References & Citations: [1]Ying Chen, et al. Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis. Mol Cancer Ther. 2010 Aug;9(8):2164-74.|[2]Qiong-Feng Chen, et al. BML-111, a Lipoxin Receptor Agonist, Protects Against Acute Injury via Regulating the Renin Angiotensin-Aldosterone System. Prostaglandins Other Lipid Mediat. 2019 Feb;140:9-17.|[3]T H Lee, et al. Inhibition of Leukotriene B4-induced Neutrophil Migration by Lipoxin A4: Structure-Function Relationships. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1416-21.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported