Anti-Corticotropin Releasing Factor Antibody

• Description:

  Mouse Monoclonal Antibody specific to Corticotropin Releasing Factor

• Product Name Alternative:

  Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone

• Gene Name:

  CRH

• NCBI Gene ID:

  CRH

• UniProt:

  P06850

• Cellular Locus:

  Secreted

• Host:

  Mouse

• Reactivity:

  Human, Rat

• Immunogen:

  Purified human/rat corticotropin-releasing factor (CRF, Sigma).

• Target Antigen:

  Corticoliberin

• Target:

  Corticotropin Releasing Factor

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Type:

  Antibody

• Applications:

  ELISA

• Field of Research:

  Neuroscience

• Purification Method:

  Purified by immunoaffinity chromatography

• Concentration:

  Lot Specific

• Dilution:

  Dilute in PBS or medium which is identical to that used in the assay system.

• Format:

  Purified

• Form:

  Liquid

• Buffer:

  Phosphate Buffered Saline

• Function:

  Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {UniProtKB:P06296, UniProtKB:Q8CIT0}.

• Additionnal Information:

  These antibodies may be used in immunoassays to detect and quantitate CRF. Other applications are under investigation.

• Storage Conditions:

  These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

• Specificity:

  These antibodies react specifically with CRF. There is no cross-reactivity with bovine serum albumin, insulin, ovalbumin, or epidermal growth factor. These two antibodies recognize different epitopes on CRF. Dissociation constants = 10-9 M for 56101and 1.5 x 10-8 M for 56102.

• Formulation:

  PBS, pH 7.4.

• Buffer pH:

  pH 7.4

• CAS Number:

  9007-83-4