Thalidomide-PEG4-NH2 (hydrochloride)
CAT:
804-HY-130964B-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-PEG4-NH2 (hydrochloride)
- CAS Number: 2387510-82-7
- UNSPSC Description: Thalidomide-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
- Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-peg4-nh2-hydrochloride.html
- Purity: 97.66
- Solubility: 10 mM in DMSO
- Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCCOCCN)=O.[H]Cl
- Molecular Weight: 485.92
- References & Citations: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. [Content Brief]
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported