GIP (1-30)-Myr

• UNSPSC Description:

  GIP (1-30)-Myr is the Myr-modified GIP (1-30), which is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) dose-dependently promotes insulin secretion over the range 10-9-10-6 M[1].

• Target Antigen:

  Insulin Receptor

• Type:

  Peptides

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gip-1-30-myr.html

• Purity:

  98.11

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCCCCCCC(NCCCC[C@@H](C(O)=O)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CC4=CNC=N4)NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CC5=CC=C(C=C5)O)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC6=CC=CC=C6)NC([C@H]([C@H](O)C)NC(CNC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](CC7=CC=C(C=C7)O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  3743.28

• References & Citations:

  [1]Alaña I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide. Biochem Biophys Res Commun. 2004 Dec 3;325(1):281-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported