Gentiopicroside (Standard)

CAT: 0804-HY-N0494R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0494R-01Size:5 mg
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Description
Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
CAS Number
[20831-76-9]
Product Name Alternative
Gentiopicrin (Standard)
UNSPSC
12352005
Target
Cytochrome P450; HCV; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gentiopicroside-standard.html
Smiles
C=C[C@@H]([C@@H]1O[C@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CO)C(C3=CO1)=CCOC3=O
Molecular Formula
C16H20O9
Molecular Weight
356.32
References & Citations
[1]Deng Y, et al. In vitro inhibition and induction of human liver cytochrome P450 enzymes by gentiopicroside: potent effect on CYP2A6. Drug Metab Pharmacokinet. 2013;28 (4) :339-44. Epub 2013 Feb 19.|[2]Yang Y, et al. Protective effect of gentiopicroside from Gentiana macrophylla Pall. in ethanol-induced gastric mucosal injury in mice. Phytother Res. 2018 Feb;32 (2) :259-266.|[3]Chen F, et al. Gentiopicroside inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and JNK signaling pathways. Biomed Pharmacother. 2018 Apr;100:142-146.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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