Balcinrenone

CAT: 0804-HY-120274-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-120274-01Size:5 mg

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Description

Balcinrenone (AZD9977) is a potent, selective, and orally active mineralocorticoid receptor (MR) modulator. Balcinrenone is used for heart failure, and chronic kidney disease research[1].

CAS Number

1850385-64-6

Product Name Alternative

AZD9977

UNSPSC

12352005

Target

Mineralocorticoid Receptor

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/balcinrenone.html

Purity

99.96

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC1=CC2=C(N(C(C3=CC=C(OCC(N4)=O)C4=C3)=O)[C@@H](CC(NC)=O)CO2)C=C1

Molecular Formula

C20H18FN3O5

Molecular Weight

399.37

References & Citations

[1]Fredrik Erlandsson, et al. Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator. Br J Clin Pharmacol. 2018 Jul;84 (7) :1486-1493.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Balcinrenone

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