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Antrafenine

CAT: 0804-HY-A0235-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0235-01Size:5 mg
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Description
Antrafenine (Stakane) is a non-narcotic analgesic. Antrafenine demonstrates central analgesic effects in acetic acid writhing test and mouse hot plate test experiments. Antrafenine significantly alleviates the pain of osteoarthritis. Antrafenine exhibits mild anti-inflammatory activity in a rat toe edema model. Antrafenine can be used in pain and anti-inflammatory research[1][2].
CAS Number
55300-29-3
Product Name Alternative
Stakane
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/antrafenine.html
Concentration
10mM
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCCN1CCN(C2=CC=CC(C(F)(F)F)=C2)CC1)C3=CC=CC=C3NC4=CC=NC5=CC(C(F)(F)F)=CC=C45
Molecular Formula
C30H26F6N4O2
Molecular Weight
588.54
Precautions
H315, H319, H320
References & Citations
[1]Manoury PM, et al. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl) alkyl 2-aminobenzoates and 2-aminonicotinates. J Med Chem. 1979;22 (5) :554-559. |[2]Berry H, et al. Antrafenine, naproxen and placebo in osteoarthritis: a comparative study. Br J Rheumatol. 1983 May;22 (2) :89-94.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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