Thiomuscimol

• Description :

  Thiomuscimol is a GABAA receptor agonist (IC50=19 nM) . It has been used as a photoaffinity label for the purification and identification of GABA binding sites within the GABAA receptor complex.

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H320

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/thiomuscimol.html

• Smiles :

  O=C1NSC(CN)=C1

• Molecular Formula :

  C4H6N2OS

• Molecular Weight :

  130.17

• Precautions :

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations :

  [1]Melikian, et al. Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists. J. Med. Chem. 35 (22), 4092-4097 (1992) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [62020-54-6]