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Isomaltulose (monohydrate)

CAT: 0804-HY-W745090Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W745090Size:1 Each
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Description
Isomaltulose monohydrate is a fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation. Isomaltulose monohydrate can interfere with the interaction between the βγ subunit of the fMLP receptor Gi protein and its downstream molecules, thereby inhibiting fMLP-induced respiratory burst. Isomaltulose monohydrate inhibits fMLP (0.1 μM) -induced superoxide anion production (IC50: 1.98 μM), cathepsin G release (IC50: 2.76 μM) and chemotaxis. Isomaltulose monohydrate can improve excessive activation of neutrophils and reduce inflammation or tissue damage. A series of derivatives of Isomaltulose monohydrate are found to have inhibitory effects on FSGS-related TRPC6 functional mutants[1].
CAS Number
58024-13-8
UNSPSC
12352200
Target
Akt; ERK; Formyl Peptide Receptor (FPR) ; p38 MAPK; Src
Type
Biochemical Assay Reagents
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/isomaltulose-monohydrate.html
Solubility
10 mM in DMSO
Smiles
OCC([C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=O.O
Molecular Formula
C12H24O12
Molecular Weight
360.31
References & Citations
[1]Lina BA, et al. Isomaltulose (Palatinose) : a review of biological and toxicological studies. Food Chem Toxicol. 2002 Oct;40 (10) :1375-81.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 3

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