FK224

CAT: 0804-HY-105264Size: InquireDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-105264Size:Inquire

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

125787-94-2

UNSPSC Description

FK224 is a tachykinin receptor antagonist. FK224 reduces the tracheal plasma extravasation induced by substance P (SP) and neurokinin A (NKA)[1].

Target Antigen

Neurokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fk224.html

Smiles

CN(C([C@H]([C@H](OC([C@@H](NC([C@@H](NC([C@](NC([C@H](NC([C@@H](NC/1=O)CC(C)C)=O)CC2=CC=CC=C2)=O)([H])[C@@H](O)C)=O)CC(N)=O)=O)CO)=O)C)NC(CCC3=C(C=CC=C3)CCCCC)=O)=O)C1=C\C4=CC=C(C=C4)O

Molecular Weight

1041.20

References & Citations

[1]Morimoto H, et al. Effects of FR 113680 and FK 224, novel tachykinin receptor antagonists, on cigarette smoke-induced rat tracheal plasma extravasation. Eur J Pharmacol. 1992 Nov 24;224(1):1-5.

Shipping Conditions

Room temperature

Clinical Information

Phase 2

FK224

Popular Products